PRE-IMPLANTATION GENETIC TESTING
Giving you peace of mind


The most well-known cause for IVF disappointment is a disappointment of implantation of the incipient organism into the coating of the uterus. There are numerous possible explanations behind this, be that as it may, chromosomal irregularity inside the early creating incipient organism is viewed as liable for most of bombed IVF cycles. In the event that an undeveloped organism contains a wrong number of chromosomes, other than the ordinary 46, it is hereditarily unusual, a condition known as aneuploidy. Hereditary testing has progressed to the degree by which we can really take a look at each chromosome inside an incipient organism and recognize any irregularities before the incipient organism is embedded once more into the body. This innovation is known as preimplantation hereditary testing for aneuploidy (PGT-A).


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    PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY (PGT-A).

    PGT-A permits us to really take a look at the number chromosomes inside every incipient organism, for instance, an undeveloped organism might have an extra duplicate of a chromosome or might be deficient with regards to a chromosome. Assuming an undeveloped organism is deficient with regards to a chromosome it is improbable that the incipient organism will embed, there are anyway a couple of exemptions, for example, Turners disorder, in which the incipient organism just holds back one sex chromosome (X0) Notwithstanding, assuming an incipient organism contains an extra duplicate of a chromosome it might in any case embed and form into a pregnancy. The most probable result for this pregnancy is that it will end in premature delivery before 12 weeks. Be that as it may, at times the pregnancy might go on further or even to full term, for instance, Down’s disorder, a condition by which the undeveloped organism has three duplicates of chromosome 21 as opposed to two. PGT-A will distinguish which incipient organisms are contain a typical arrangement of chromosomes (46) and are euploid and which undeveloped organisms contain a strange arrangement of chromosomes (+/ – 46) and are aneuploid. Distributed information has exhibited that if an euploid incipient organism (chromosomally typical) is gotten once again to the belly the probability of a fruitful result is more noteworthy than the exchange of an unscreened undeveloped organism through IVF. Nonetheless, PGT-An isn’t required for everybody; at Aria our experts will examine with you whether this ripeness treatment is a choice to help you start or keep on developing your loved ones.

    PREIMPLANTATION GENETIC TESTING FOR MONOGENIC DISEASES (PGT-M)

    For certain families having a child can be confounded not by fruitlessness but rather on the grounds that one of the accomplices, or the two accomplices convey a particular acquired hereditary condition which could be possibly gone to any kid.

    Will I want PGT-M?

    PGT-M is an expert treatment and may be required if you, your accomplice or the both of you are a known transporter of a hereditary condition. The beneath list contains a couple of instances of the sorts of patients we can assist with treating utilizing the PGT-M innovation:

    • Families who have had a kid or pregnancy which has been impacted with a solitary quality problem.
    • The two accomplices are known to be transporters of a similar autosomal latent condition, like Cystic Fibrosis.
    • A Transporter Hereditary Test (CGT) is a hereditary test you might wish to have prior to beginning a family.

    This test evaluates the two accomplices for a scope of passive hereditary infections and assists with deciding whether there is a gamble of having a kid with a hereditary illness. A predominant acquired hereditary condition might have been analyzed in your loved ones. If so there is a half possibility passing the transformed quality onto every kid for example Huntington infection.

    Either accomplice is a known transporter of a X-connected condition, like Duchenne Strong Dystrophy. Families who have a past filled with an inherited malignant growth condition, like bosom disease (BRCA1 and 2), brought about by single quality change.

    These hereditary circumstances are known as single-quality problems, for instance, Cystic Fibrosis, alpha or beta Thalassemia or sickle cell pallor are probably the most well-known. There are numerous other single-quality problems which can have destroying outcomes in the event that these are gone to any youngster. There are more than 600 distinct sorts of predominant and passive hereditary illnesses which we can test for. A rundown of all the single-quality problems were are presently authorized by the HFEA to have the option to test for can be seen as here.

    Utilizing PGT-M innovation we can evaluate each undeveloped organism for the presence or nonattendance of a solitary quality problem. Thusly, we just supplant undeveloped organisms which are unaffected with the specific hereditary infection back into the body so a sound pregnancy can be considered.

    PREIMPLANTATION GENETIC TESTING FOR STRUCTURAL REARRANGEMENTS (PGT-SR)

    Underlying chromosomal revisions are transformations of the chromosomes including an adjustment of the regular chromosome size or game plan. If either accomplice has been determined to have a primary revision of their chromosomes there is a fundamentally higher possibility of a pregnancy finishing off with unnatural birth cycle or having a kid which acquires a hereditary problem.

    Many individuals who convey a fair type of a primary revision, are much of the time solid and uninformed that they are a transporter of this hereditary condition, until they begin to pursue a family.

    The PGT-SR process expects that we screen each of the undeveloped organisms made through the IVF interaction to guarantee that they have acquired the right measure of hereditary material. We can then supplant any incipient organisms which have been unaffected by the primary irregularity and are probably going to frame an effective pregnancy.

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